Fig. 4
From: High-throughput high-volume nuclear imaging for preclinical in vivo compound screening§
Bland-Altman plots on the difference in tumour data between ex vivo (dissected tissue) and in vivo (SPECT/CT) methods, based on pairs of data from the same animal. Left panel, tumour weight (ex vivo) and tumour volume (SPECT ROI) (converted to weight assuming tissue density = 1.0 g/mL); right panel, radiotracer uptake in tumour as % ID (ex vivo from gamma counting and in vivo from SPECT ROI). Bias as dotted line (at −80 mg and +0.14% ID, respectively), 95% agreement interval as pair of bold dotted lines. Values on the abscissa are individual tumour averages over the two measurement methods