Table 4 Bland-Altman analysis of VT, DVR–1 and BPND of animal data
From: Pharmacokinetic modeling of [11C]flumazenil kinetics in the rat brain
Animal data | |||
|---|---|---|---|
% difference (95% L.A.) | |||
VT | 1TCM | SA | 2TCMa |
Frontal cortex | −0.20 (−1.93 to 1.52) | −5.16 (−18.2 to 7.87) | – |
Hippocampus | −0.32 (−2.50 to 1.84) | −1.43 (−10.0 to 7.15) | – |
Cerebellum | −8.01 (−19.0 to 3.01) | −1.31 (−5.42 to 2.78) | – |
Medulla | −16.9 (−34.0 to 0.24) | −3.54 (−14.4 to 7.32) | – |
Pons | −19.1 (−35.9 to −2.37) | 0.44 (−24.2 to 25.0) | – |
Overall | −8.91 (−28.4 to 10.5) | −2.20 (−16.2 to 11.8) | – |
DVR–1 | 1TCM | SA | |
Frontal cortex | 26.7 (4.74 to 48.7) | −9.01 (−53.3 to 35.3) | – |
Hippocampus | 28.3 (5.72 to 50.8) | −2.53 (−31.5 to 26.4) | – |
Cerebellum | 24.1 (4.75 to 43.2) | 1.70 (−22.8 to 26.2) | – |
Medulla | 28.5 (−44.7 to 101) | −7.02 (−49.3 to 35.3) | – |
Pons | – | – | – |
Overall | 26.9 (−12.6 to 66.4) | −4.21 (−39.8 to 31.4) | – |
BPND | FRTM | SRTM | SRTM-2C |
Frontal cortex | −12.5 (−20.3 to −4.67) | −13.8 (−21.5 to 6.16) | −7.74 (−15.3 to −0.22) |
Hippocampus | −11.0 (−17.9 to −4.05) | −12.5 (−19.6 to −5.40) | −7.59 (−12.9 to −2.24) |
Cerebellum | −6.54 (−15.9 to 2.82) | −9.58 (−22.3 to 3.14) | −13.7 (−29.1 to 1.72) |
Medulla | −25.6 (−152 to 101) | −27.7 (−134 to 78.8) | −66.2 (−151 to 18.8) |
Pons | – | – | – |
Overall | −13.9 (−76.7 to 48.9) | −15.9 (−69.6 to 37.8) | −23.8 (−88.0 to 40.4) |