Fig. 4

Model preference (based on AIC) of simulated TACs. A figure on model preference for simulated TACs of increasing specific binding and noise levels. On the left, a plot of AIC values for the 1TCM (black) and the 2TCM (gray) for simulated noiseless TACs with increasing levels of specific-binding (increasing k₃, x-axis). The two graphs on the right represent mean ± SD (solid line, dashed lines) for the AIC values of 1TCM (black) and 2TCM (gray) fits with 5 and 10% added noise