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Table 2 The image features used in this study. For the column of “image modality”, the term “PET/CT” means the feature is calculated for both PET and CT

From: Comparison of machine learning methods for classifying mediastinal lymph node metastasis of non-small cell lung cancer from 18F-FDG PET/CT images

Feature

Image modality

Spatial dimension

Definition

D short

PET/CT

1D

Diagnostic feature, maximum short diameter of the axial section

Area

PET/CT

2D

Diagnostic feature, area of the axial section

Volume

PET/CT

3D

Diagnostic feature, volume of the lymph node

CTmean

CT

2D/3D

Diagnostic feature, mean CT value inside the lymph node

CTcontrast

CT

2D/3D

Diagnostic feature, the difference between CTmean and the mean CT value of a 2-mm-thick tissue layer surrounding the lymph node.

SUVmean

PET

2D/3D

Diagnostic feature, mean SUV inside the lymph node

SUVmax

PET

2D/3D

Diagnostic feature, max SUV inside the lymph node

SUVstd

PET

2D/3D

Diagnostic feature, standard deviation of SUV inside the lymph node

1st-order texture features

PET/CT

3D

Six texture features calculated based on the pixel intensity histogram, see the supplementary material of [22] for detailed definition

2nd-order texture features

PET/CT

2D

Nineteen texture features calculated based on gray-level co-occurrence matrix (GLCM), see the supplementary material of [22] for detailed definition

High-order texture features

PET/CT

3D

Five texture features calculated based on neighborhood gray-tone difference matrix (NGTDM) and 11 texture features calculated based on gray-level zone size matrix (GLZSM), see the supplementary material of [22] for detailed definition

  1. For the column of “spatial dimension”, the term “2D/3D” means the feature is calculated for both 2D and 3D images