Table 3 Tumor-to-background ratios obtained in PC-3 PIP/flu tumor-bearing mice

PSMA-ligand

⁴⁴Sc-PSMA-617

¹⁷⁷Lu-PSMA-617

⁶⁸Ga-PSMA-617

⁶⁸Ga-PSMA-11

 Tumor-to-blood

5.38 ± 0.90

4.45 ± 0.66

4.15 ± 0.24

6.10 ± 1.84

 Tumor-to-liver

18.8 ± 5.02

20.4 ± 5.48

6.02 ± 0.59

15.3 ± 3.96

 Tumor-to-kidney

0.97 ± 0.21

1.06 ± 0.14

1.26 ± 0.25

0.41 ± 0.14

⁴⁴Sc-PSMA-617

¹⁷⁷Lu-PSMA-617

⁶⁸Ga-PSMA-617

⁶⁸Ga-PSMA-11

 Tumor-to-blood

17.6 ± 1.23

16.0 ± 3.52

16.9 ± 4.22

20.5 ± 6.40

 Tumor-to-liver

55.6 ± 7.36

53.1 ± 6.68

19.0 ± 2.32

31.7 ± 2.48

 Tumor-to-kidney

1.60 ± 0.22

2.09 ± 0.24

3.62 ± 0.81

0.58 ± 0.10

⁴⁴Sc-PSMA-617

¹⁷⁷Lu-PSMA-617

⁶⁸Ga-PSMA-617

⁶⁸Ga-PSMA-11

 Tumor-to-blood

>200

>200

>200

>200

 Tumor-to-liver

>200

>200

35.2 ± 9.94

71.3 ± 7.48

 Tumor-to-kidney

7.98 ± 1.71

11.6 ± 0.87

15.9 ± 3.26

0.69 ± 0.12