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Table 2 Summary of the organ doses, expressed per injected MBq of 99mTc-labelled S-HYNIC CZP as well as for the total mean administered activity of 690 MBq

From: 99mTc-labelled S-HYNIC certolizumab pegol in rheumatoid arthritis and spondyloarthritis patients: a biodistribution and dosimetry study

Organs

Organ dose

μGy/MBq

Mean and SD

Total organ dose

mGy

Mean and SD

Brain

1.3

0.5

0.9

0.3

Skin

1.8

0.3

1.2

0.2

Thyroid

2.1

0.4

1.4

0.3

Uterus

4.6

0.5

3.3

0.4

Ovaries

3.9

0.5

2.7

0.4

Testes

1.7

0.5

1.1

0.4

Breasts

3.7

0.5

2.5

0.4

Red marrow

3.8

0.4

2.6

0.3

Muscle

3.5

0.5

2.4

0.3

Small intestine

4.3

0.6

3.0

0.4

ULI wall

4.9

0.7

3.4

0.5

LLI wall

3.1

0.7

2.2

0.5

Stomach wall

6.3

1.0

4.3

0.7

Thymus

6.9

0.8

4.7

0.5

Osteogenic cells

7.4

1.4

5.1

1.0

Pancreas

10.8

1.6

7.4

1.1

Adrenals

11.2

1.7

7.7

1.2

Gallbladder wall

11.9

1.8

8.2

1.2

Lungs

18.6

2.7

12.8

1.9

Urinary bladder wall

19.9

8.3

13.7

5.8

Heart wall

30.6

5.1

21.1

3.5

Liver

32.7

6.9

22.5

4.7

Spleen

34.0

6.2

23.4

4.3

Kidneys

56.1

7.3

38.7

5.1