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EJNMMI Research
Fig. 7 | EJNMMI Research

Fig. 7

From: Low kidney uptake of GLP-1R-targeting, beta cell-specific PET tracer, 18F-labeled [Nle14,Lys40]exendin-4 analog, shows promise for clinical imaging

Fig. 7

In vitro and ex vivo binding of [18F]exendin-4 in rat brain. a GLP-1R was clearly labeled in the lateral septum (LS) after incubating sections of rat brain with tracer in vitro (1.25 nM). b No binding in the corresponding brain area was observed 60 min after intravenous injection of [18F]exendin-4 (50 MBq). c For histological reference, the same section was stained with hematoxylin and eosin (HE). Scale bar 1000 μm

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