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Table 1 Test-retest analysis of unadjusted SUV

From: Test-retest analysis of a non-invasive method of quantifying [11C]-PBR28 binding in Alzheimer’s disease

 

Mean test value

Mean retest

Mean regional difference % (SD)

Mean VAR % (SD)a

ICC

Sample size to detect 5 % changeb

Sample size to detect 10 % changeb

Frontal lobe

1.22

1.24

1.40

(6.62)

−1.22

(6.50)

0.96

21

7

Parietal lobe

1.17

1.19

2.33

(7.61)

−2.08

(7.49)

0.94

27

9

Temporal lobe

1.17

1.18

0.98

(7.34)

−0.76

(7.27)

0.93

25

8

Occipital lobe

1.21

1.22

0.87

(8.07)

−0.61

(8.10)

0.93

30

9

Hippocampus

1.06

1.08

2.01

(6.55)

−1.82

(6.48)

0.93

21

7

Parahippocampal cortex

1.15

1.18

2.91

(6.27)

−2.72

(6.08)

0.97

19

7

Posterior cingulate

1.31

1.35

3.27

(7.20)

−3.02

(7.03)

0.95

24

8

Amygdala

1.22

1.22

1.49

(6.01)

−1.34

(5.73)

0.98

18

7

Cerebellum

1.32

1.29

−1.81

(10.22)

2.28

(10.93)

0.87

45

14

Whole brain

1.13

1.14

1.35

(7.30)

−1.13

(7.22)

0.94

25

8

Mean

(SD)

1.20

(0.08)

1.21

(0.08)

1.48

(7.32)

−1.24

(7.28)

0.94

26

8

  1. ICC intraclass correlation coefficient
  2. aVAR = absolute variability (%)
  3. bModel parameters: two-tailed, power 0.9, alpha 0.05