Table 1 A summary of the definitions of measurability and response categories
Visual evaluation | PERCIST 1.0 | |
|---|---|---|
Measurable lesions | FDG avid above background | SUL peak at least 1.5 times SULmean liver + 2 SD |
CMR* | FDG avid lesions revert to background of normal tissue in which they are located | Disappearance of all measurable lesion to background blood-pool levels |
PMR* | Significant reduction in intensity of tumor metabolic activity | Reductions of min. 30 % in target SULpeak, with an absolute drop of at least 0.8. No new lesions |
SMD* | No visible change in metabolic activity of tumors | Not CMR, PMR, or PMD |
PMD* | Increase in intensity or extent of tumor metabolic activity or new lesions typical for cancer | More than 30 % increase in target SULpeak, with an absolute increase of at least 0.8. Or visible increase in extent without drop in SULpeak. Or appearance of new FDG avid lesions typical of cancer, not related to treatment or infection |