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EJNMMI Research

Table 3 Precision and accuracy of plasma thymidine assay; acceptance criteria ±15 % for CV and RE (±20 % at LLOQ)

From: The relationship between endogenous thymidine concentrations and [18F]FLT uptake in a range of preclinical tumour models

QC

Theoretical thymidine concentration (ng/mL)

Calculated thymidine mean concentration (ng/mL, n = 6)

CV (%)

RE (%)

LLOQ

1

0.99a

19

−0.9

Low

3

2.81

10

−6.4

Medium

40

47

13

−5.4

High

450

462

1.7

2.6

  1. LLOQ Lower limit of quantification, CV coefficient of variation, RE relative error
  2. a n = 5
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