Table 2 Summary of imaging parameters at each centre
Research Centre | Injected dose (average, MBq) | Measurement time | PET scanner | Reconstruction method |
|---|---|---|---|---|
CRUK Cambridge Institute (CI) | 8.3 | 60–65 min | NanoScan PET/CT pre-clinical PET scanner (Mediso) | 3D OSEM |
AstraZeneca (AZ) | 8.3 | 50–60 min | Inveon Siemens PET scanner | 2D FBP |
Imperial College London (IC) | 3.7 | 50–60 min | Inveon Siemens PET scanner | 2D OSEM |
WMIC Manchester | 9.5 | 57.5–62.5 and 55–65 min (FCT113 only) | quadHIDAC small animal PET scanner (Oxford Positron Systems) or Inveon Siemens PET scanner (U87 and FCT113 only) | OPL-EM or 3D-OSEM/MAP |