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Table 1 Comparison of the effect of chemotherapy on the primary tumor measured with 18F-FAZA and 18F-FDG PET including tumor response in non-small-cell lung cancer

From: An exploratory study of volumetric analysis for assessing tumor response with 18F-FAZA PET/CT in patients with advanced non-small-cell lung cancer (NSCLC)

Patient Age Sex 18F-FAZA (T/Bg ratio)a 18F-FDG (SUVmax)b Fractional hypoxic volume CT scan
    Baseline 2 cycles Baseline 2 cycles Baseline 2 cycles  
1 56 F 7.1 5.0 32.5 24.2 96 % 100 % PD
2 43 M 3.0 2.0 15.4 2.1 98 % 9 % SD
3 45 F 4.4 3.3 27.3 18.2 95 % 95 % PD
4 52 F 7.7 7.7 5.8 c 100 % 97 % SD
5 48 F 2.9 2.6 7.2 5.9 63 % 30 % SD
6 61 M 6.7 4.7 15.8 4.4 100 % 100 % SD
7 62 F 3.3 5.4 8.9 6.0 58 % 100 % PR
  1. PR partial response, SD stabile disease, PD progressive disease
  2. aUptake for the whole primary tumor was corrected for partial volume effect. It was then divided by the mean of the background activity and this is tumor to background (T/Bg) value
  3. bUptake for the whole primary tumor, expressed in SUV, were corrected for partial volume effect
  4. cDue to a dosimeter error, not usable for qualitative comparison