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Table 2 Parameter values fitted to the premature infants and newborns to 5-year-olds FDG model

From: Pharmacokinetic modeling of [18F]fluorodeoxyglucose (FDG) for premature infants, and newborns through 5-year-olds

Parameter

Premature

0- to 5-year-olds

Adults

Plasma to erythrocytes (k1)

5.82E−02

5.31E−04

4.80E+00

Erythrocytes to plasma (k2)

1.16E−01

6.88E+01

8.07E+00

Plasma to fast brain (k3)

6.12E−02

3.70E−03

1.02E−01

Fast brain to plasma (k4)

1.30E−01

1.00E−01

1.30E−01

Fast brain to slow brain (k5)

6.62E−02

1.00E+00

6.20E−02

Slow brain to fast brain (k6)

9.57E−04

9.57E−04

6.80E−03

Plasma to lungs (k7)

7.20E−04

5.00E−06

1.70E−03

Lungs to plasma (k8)

6.46E−04

6.50E−04

Plasma to heart wall (k9)

1.72E−04

8.00E−07

5.30E−03

Heart wall to plasma (k10)

1.16E−07

5.50E−01

Plasma to kidneys (k11)

7.57E−04

2.75E−03

Kidneys to plasma (k12)

2.26E−02

5.50E−02

Plasma to fast liver (k13)

1.72E−02

2.00E−02

6.80E−02

Fast liver to plasma (k14)

2.19E−02

3.00E+00

2.19E−01

Fast liver to slow liver (k15)

1.20E−06

1.50E−03

1.80E−02

Plasma to fast “other” (k16)

1.32E+00

4.20E−02

3.71E−01

Fast “other” to plasma (k17)

2.76E+00

8.90E−02

1.02E−01

Fast “other” to slow “other” (k18)

3.62E−03

9.47E−03

1.67E−02

Blood volume fraction in brain

2.20E−02

1.35E−01

2.20E−01

Blood volume fraction in lungs

9.00E−02

3.00E−02

1.50E−01

Blood volume fraction in heart

2.50E−02

3.10E−02

6.90E−02

Blood volume fraction in liver

9.80E−02

2.43E−01