Table 4 Time-stability of regional V T values for [11C]TASP0410457 in the monkey brain
| Â | Logan graphical analysis | One-tissue compartment model | |||
|---|---|---|---|---|---|
| Â | Scan duration (min) | Scan duration (min) | |||
Region | 60 | 70 | 80 | 90 | 90 |
Striatum | 21.2 ± 3.0 | 21.5 ± 3.0 | 21.9 ± 3.3 | 22.6 ± 3.8 | 23.2 ± 3.6 |
Anterior cingulate cortex | 18.4 ± 2.7 | 18.6 ± 2.8 | 19.1 ± 3.2 | 19.5 ± 3.4 | 20.3 ± 3.3 |
Thalamus | 15.1 ± 1.7 | 15.4 ± 1.9 | 15.6 ± 1.9 | 16.0 ± 2.1 | 16.1 ± 1.8 |
Hippocampus | 13.0 ± 1.0 | 13.2 ± 1.0 | 13.6 ± 1.2 | 13.9 ± 1.4 | 13.9 ± 1.3 |
Frontal cortex | 12.3 ± 1.6 | 12.5 ± 1.7 | 12.8 ± 1.8 | 13.0 ± 2.0 | 13.4 ± 1.8 |
Cerebellum | 12.1 ± 1.2 | 12.4 ± 1.3 | 12.7 ± 1.5 | 13.0 ± 1.7 | 12.8 ± 1.7 |
Temporal cortex | 12.3 ± 1.6 | 12.4 ± 1.7 | 12.5 ± 1.8 | 12.9 ± 2.1 | 13.3 ± 2.1 |
Occipital cortex | 11.7 ± 1.6 | 11.8 ± 1.6 | 12.0 ± 1.8 | 12.1 ± 1.9 | 12.7 ± 2.0 |
Pons-medulla | 8.5 ± 0.6 | 8.6 ± 0.7 | 8.8 ± 0.7 | 9.1 ± 0.9 | 8.8 ± 0.9 |