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Fig. 3 | EJNMMI Research

Fig. 3

From: Impact of clinically tested NEP/ACE inhibitors on tumor uptake of [111In-DOTA]MG11—first estimates for clinical translation

Fig. 3

a Uptake of [111In-DOTA]MG11 in kidneys and AR42J tumors at 4 h pi in SCID mice. Data are given for kidneys and tumors as mean of %ID/g ± SD, n ≥ 4; [111In-DOTA]MG11 iv-coinjection with vehicle (), with 100 μg Lis (), with 300 μg PA (), with a mixture of 100 μg Lis and 300 μg PA (), with 150 μg TO (), or 30–40 min after ip injection of 3 mg Race (); for CCK2R blockade, 40 nmol DG2 [25] was iv-coinjected along with 300 μg PA (). b Corresponding tumor-to-kidney ratios (Tu/Ki)

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