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EJNMMI Research
Fig. 5 | EJNMMI Research

Fig. 5

From: Modeling [18F]-FDG lymphoid tissue kinetics to characterize nonhuman primate immune response to Middle East respiratory syndrome-coronavirus aerosol challenge

Fig. 5

Patlak plots generated from IDIF and TACs from mediastinal (a) and axillary (b) LNs and bone marrow (c) on day 7 after MERS-CoV exposure in one representative animal. Green dots represent the experimental curve. Tissue [18F]-FDG net uptake rate (K i ) is calculated as a slope of computed regression line (orange triangles and solid lines). For constant [18F]-FDG levels in arterial blood during the late phase, normalized time is identical to the true imaging time. Abbreviations: FDG, fluorodeoxyglucose; IDIF, image-derived input function; TACs, time activity curves

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