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Table 3 Method III—multiple of liver mean activity + 2 × standard deviation (SD))

From: Optimal definition of biological tumor volume using positron emission tomography in an animal model

Multiple of liver mean Sensitivity (CI) Specificity (CI) GTAOE/WTAH (CI)
1.5 100.0 % (100.0–100.0 %) 11.9 % (6.9–17.7 %) 50.5 % (42.7–59.1 %)
3 99.9 % (99.7–100.0 %) 36.9 % (26.8–47.1 %) 24.4 % (20.0–29.2 %)
4 99.3 % (98.8–99.6 %) 50.8 % (40.4–60.6 %) 16.2 % (13.0–19.8 %)
5 97.8 % (96.8–98.6 %) 62.1 % (53.0–70.7 %) 11.1 % (8.7–13.9 %)
6 95.1 % (93.5–96.5 %) 71.2 % (63.4–78.5 %) 7.4 % (5.6–9.5 %)
7 90.7 % (88.1–93.2 %) 78.1 % (71.5–84.3 %) 5.1 % (3.7–6.9 %)
  1. CI confidence interval, GTA OE gross tumor area overestimate, WTA H whole tumor areas on histology