Fig. 3
From: Optimal definition of biological tumor volume using positron emission tomography in an animal model
Pathological specimen. a A paraffin tumor tissue block with central necrosis (marked in yellow square) from reference rat 9 (Top) and its corresponding H&E stain (bottom). b The center of the H&E stain in ×20 magnification. There is a pathological correlation between the necrotic center on the H&E stain and the macroscopic morphology of the central necrosis (marked in yellow square) in the tissue block in Fig. 2 a. c The center of the H&E stain in ×80 magnification. The central necrotic area consists of hemorrhage, cell debris, and neutrophil infiltration