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Fig. 2 | EJNMMI Research

Fig. 2

From: Development of a clickable bimodal fluorescent/PET probe for in vivo imaging

Fig. 2

Synthesis and analytical data of 18F-BODIPY-BBN 3. a Tin tetrachloride-catalyzed 18F-radiolabeling of BODIPY-Fl azide 1 followed by CuAAC click chemistry with alkyne-modified bombesin analog (RM2-alkyne) to yield 18F-BODIPY-BBN 3. b HPLC chromatograms (radio trace and absorbance at 500 nm) of 18F-BODIPY-N3 2 (left) and 18F-BODIPY-BBN 3 (right). c Electrospray ionization mass spectrometry of cold BODIPY-BBN

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