Absorption, distribution and excretion of intravenously injected 68Ge/68Ga generator eluate in healthy rats, and estimation of human radiation dosimetry

EJNMMI Research

Table 5 Additional dosimetry estimates based on a female rat distribution data

	Absorbed dose per unit radioactivity administered (mSv/MBq)
Organ	15-year-olds	10-year-olds	5-year-olds	1-year-olds	Newborn
Organ	(50 kg)	(30 kg)	(17 kg)	(10 kg)	(5 kg)
Adrenals	0.0220	0.0337	0.0521	0.0922	0.212
Brain	0.00526	0.00685	0.00531	0.0148	0.0333
Breasts	0.0178	0.0304	0.0483	0.0885	0.211
Gallbladder wall	0.0194	0.0307	0.0466	0.0875	0.217
Lower large intestine wall	0.0144	0.0236	0.0374	0.0696	0.176
Small intestine	0.0157	0.0251	0.0400	0.0762	0.182
Stomach wall	0.0187	0.0285	0.0451	0.0849	0.202
Upper large intestine wall	0.0153	0.0247	0.0400	0.0754	0.185
Heart wall	0.576	0.893	1.44	2.61	5.11
Kidneys	0.0363	0.0521	0.0777	0.139	0.351
Liver	0.0722	0.109	0.164	0.315	0.721
Lungs	0.0575	0.0823	0.125	0.239	0.611
Muscle	0.0201	0.0382	0.109	0.215	0.305
Ovaries	0.0349	0.0893	0.1550	0.349	0.710
Pancreas	0.0335	0.0608	0.0823	0.166	0.496
Red marrow	0.0262	0.0455	0.0828	0.201	0.737
Osteogenic cells	0.0745	0.117	0.194	0.452	1.39
Skin	0.0116	0.0187	0.0306	0.0595	0.151
Spleen	0.0391	0.0602	0.0955	0.174	0.449
Testes	0.0126	0.0203	0.0327	0.0637	0.156
Thymus	0.0311	0.0413	0.0622	0.107	0.237
Thyroid	0.0342	0.0537	0.113	0.213	0.314
Urinary bladder wall	0.0733	0.113	0.180	0.345	0.895
Uterus	0.0118	0.0721	0.110	0.198	0.136
Total body	0.0258	0.0420	0.0678	0.133	0.338
Effective dose (mSv/MBq)	0.03110	0.0582	0.096800	0.20100	0.48500