Skip to main content

Advertisement

Table 1 Biodistribution data (%ID/g) of [ 18 F]-7B in FVB mice ( n = 3)

From: Synthesis, characterization, and preclinical validation of a PET radiopharmaceutical for interrogating Aβ (β-amyloid) plaques in Alzheimer’s disease

Organ (%ID/g) 5.00 min 30.00 min 60.00 min 120.00 min
Blood 3.18 ± 0.23 2.51 ± 0.09 2.40 ± 0.17 1.86 ± 0.05
Brain 7.23 ± 0.47 2.27 ± 0.13 2.00 ± 0.15 1.55 ± 0.01
Bone 1.61 ± 0.20 2.08 ± 0.13 3.41 ± 0.37 5.27 ± 0.34
Liver 16.22 ± 1.43 5.21 ± 0.08 3.44 ± 0.20 2.73 ± 0.16
Kidney 6.72 ± 0.44 2.83 ± 0.09 2.20 ± 0.07 1.59 ± 0.03
  1. %ID, percentage injected dose.