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Table 3 Crosstabs on SSTR 2 immunohistochemistry (IHC) against molecular markers, histological type, and tumor grade

From: Somatostatin receptor subtype 2 in high-grade gliomas: PET/CT with 68Ga-DOTA-peptides, correlation to prognostic markers, and implications for targeted radiotherapy

 

SSTR 2 IHC

Negative

Positive

P value

n (%)

n (%)

 

IDH1 mutation

   

 Yes

3 (33.3)

6 (66.7)

0.007

 No

16 (84.2)

3 (15.8)

 

1p/19q co-deletion

   

 Yes

2 (50.0)

2 (50.0)

0.409

 No

17 (70.8)

7 (29.2)

 

EGFR amplification

   

 Yes

8 (100.0)

0 (0.0)

0.021

 No

11 (55.0)

9 (45.0)

 

MGMT promoter methylation

   

 Yes

13 (59.1)

9 (40.9)

0.080

 No

5 (100.0)

0 (0.0)

 

p53 mutation

   

 Yes

11 (78.6)

3 (21.4)

0.225

 No

8 (57.1)

6 (42.9)

 

Grade

   

 III

6 (42.9)

8 (57.1)

0.005

 IV

13 (92.9)

1 (7.1)

 

Oligodendroglioma component

   

 Yes

2 (28.6)

5 (71.4)

0.010

 No

17 (81.0)

4 (19.0)