Skip to main content

Advertisement

Table 3 Crosstabs on SSTR 2 immunohistochemistry (IHC) against molecular markers, histological type, and tumor grade

From: Somatostatin receptor subtype 2 in high-grade gliomas: PET/CT with 68Ga-DOTA-peptides, correlation to prognostic markers, and implications for targeted radiotherapy

  SSTR 2 IHC
Negative Positive P value
n (%) n (%)  
IDH1 mutation    
 Yes 3 (33.3) 6 (66.7) 0.007
 No 16 (84.2) 3 (15.8)  
1p/19q co-deletion    
 Yes 2 (50.0) 2 (50.0) 0.409
 No 17 (70.8) 7 (29.2)  
EGFR amplification    
 Yes 8 (100.0) 0 (0.0) 0.021
 No 11 (55.0) 9 (45.0)  
MGMT promoter methylation    
 Yes 13 (59.1) 9 (40.9) 0.080
 No 5 (100.0) 0 (0.0)  
p53 mutation    
 Yes 11 (78.6) 3 (21.4) 0.225
 No 8 (57.1) 6 (42.9)  
Grade    
 III 6 (42.9) 8 (57.1) 0.005
 IV 13 (92.9) 1 (7.1)  
Oligodendroglioma component    
 Yes 2 (28.6) 5 (71.4) 0.010
 No 17 (81.0) 4 (19.0)