Table 2 Affinity profiles of the nat Ga, nat Lu, and nat Y complexes of DOTATATE and HA-DOTATATE for hsst 1 -hsst 5 receptors
Peptide | hsst 1 | hsst 2 | hsst 3 | hsst 4 | hsst 5 |
|---|---|---|---|---|---|
natGa-DOTATATE | >1,000 (2) | 1.2 ± 0.6 (5) | >1,000 (2) | >1,000 (3) | >1,000 (3) |
natLu-DOTATATE | >1,000 (2) | 2.0 ± 0.8 (5) | 162 ± 16 (2) | >1,000 (3) | >1,000 (3) |
natGa-HA-DOTATATE | >1,000 (2) | 1.4 ± 0.8 (5) | >1,000 (2) | >1,000 (3) | 102 ± 65 (4) |
natLu-HA-DOTATATE | >1,000 (2) | 2.0 ± 1.6 (5) | 93 ± 1 (2) | >1,000 (3) | 222 ± 148 (4) |
natY-HA-DOTATATE | n.d. | 2.4 ± 0.3 (2) | n.d. | n.d. | 680 (1) |