Scheme 2From: A comparative PET imaging study with the reversible and irreversible EGFR tyrosine kinase inhibitors [11C]erlotinib and [18F]afatinib in lung cancer-bearing mice Radiosynthesis of [ 18 F]6 and subsequent condensation towards [ 18 F]afatinib. MeCN, acetonitrile; MeOH, methanol; DBU, 1,8-diazabicyclo[5.4.0]undec-7-een; NMP, N-methylpyrrolidone.Back to article page