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Table 3 Conclusions of Japanese studies compared with those of international HTA reports

From: An assessment of the characteristics and quality of diagnostic accuracy studies for positron emission tomography conducted in Japan: a systematic review

Diseases

Number of studies

Mean quality score

Comparative study (%)

Positive conclusion* (%)

International HTA report

Recommendation of PET use in oncology

Lung cancer

30

7.2

11 (37)

8 (27)

â—‹ (SNP, NCLC)

Yes (SNP, NCLC)

Lymphoma

5

6

4 (80)

3 (60)

Ă—

No

Head and neck cancer

12

6.7

5 (42)

5 (42)

â—‹

Yes

Colorectal cancer

8

6.6

3 (38)

4 (50)

Ă—

No

Breast cancer

10

5.7

4 (40)

3 (30)

Ă—

No

Esophageal cancer

4

8.8

3 (75)

1 (25)

Lack of evidence

No

Stomach cancer

4

5.8

2 (50)

3 (75)

Lack of evidence

-

Pancreatic cancer

6

8.7

4 (67)

4 (67)

Unclear

Yes

Cervical cancer

4

7.5

3 (75)

3 (75)

Lack of evidence

-

Ovarian cancer

4

6.3

4 (100)

3 (75)

â—‹

-

Uterine cancer

6

7.8

3 (50)

0 (0)

Lack of evidence

-

  1. *Positive: PET(/CT) was superior to other competitive diagnostic technologies.
  2. â—‹, evidence for diagnostic accuracy; Ă—, non-evidence for diagnostic accuracy; SNP, solitary pulmonary nodule; NCLC, non-small-cell lung cancer.