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Table 1 Organ biodistribution of IG3

From: Labeling galectin-3 for the assessment of myocardial infarction in rats

 

Control

2 W-MI

4 W-MI

MI infarct (apex)

0.058 ± 0.039

0.151 ± 0.047

0.071 ± 0.059

MI border

0.047 ± 0.028

0.110 ± 0.021*

0.056 ± 0.044

MI remote

0.045 ± 0.033

0.108 ± 0.026*

0.055 ± 0.044

Lung

0.094 ± 0.034

0.194 ± 0.055

0.093 ± 0.073

Liver

0.236 ± 0.249

0.519 ± 0.095

0.192 ± 0.198

Spleen

0.079 ± 0.035

0.356 ± 0.041Φ

0.134 ± 0.118

Kidney

0.502 ± 0.101

0.784 ± 0.149

0.693 ± 0.367

Bone

0.057 ± 0.025

0.070 ± 0.013

0.053 ± 0.034

Thyroid

1.126 ± 1.409

1.326 ± 0.298

1.342 ± 0.223

Muscle

0.015 ± 0.004

0.021 ± 0.001

0.022 ± 0.013

  1. Data are presented as %ID/g (mean ± SD) 4 h after injection.
  2. %ID/g, percent injected dose per gram; MI, myocardial infarction; 2 W-MI, myocardial infarction 2 weeks old; 4 W-MI, myocardial infarction 4 weeks old.
  3. *p < 0.05 control vs. 2 W-MI rats.
  4. p < 0.01 control vs. 2 W-MI rats.
  5. Φp = 0.0571 2 W-MI vs. control and 2 W-MI vs. 4 W-MI rats.