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Table 3 Results of scintigraphic and biochemical parameters in CSA and TAC groups at 1-year control

From: Cyclosporin A, but not tacrolimus, negatively affects the hepatic extraction fraction of hepatobiliary scintigraphy in liver transplant recipients

Parameters (range, average ± SD)

Total (n  = 38)

CSA at 1 year (n  = 21)

TAC at 1 year (n  = 17)

pvalue

HEF (%)

17 to 100

17 to 79

37 to 100

<0.0001

62.8 ± 29.0

44.7 ± 18.4

85.2 ± 23.6

Bilirubin (μmol/l)

3.0 to 146.0

4.0 to 146.0

3.0 to 142.0

0.88

18.5 ± 30.4

17.8 ± 29.9

19.4 ± 32.0

ALAT (μkat/l)

0.2 to 3.9

0.2 to 3.0

0.2 to 3.9

0.13

1.1 ± 1.0

0.8 ± 0.7

1.3 ± 1.2

ASAT (μkat/l)

0.3 to 3.0

0.3 to 2.4

0.3 to 3.0

0.38

0.9 ± 0.7

0.8 ± 0.5

1.0 ± 0.9

ALP (μkat/l)

0.7 to 5.8

0.7 to 5.8

0.8 to 4.8

0.44

1.8 ± 1.0

1.9 ± 1.4

1.7 ± 1.0

GT (μkat/l)

0.2 to 26.2

0.4 to 8.1

0.2 to 26.2

0.12

3.2 ± 5.1

2.1 ± 2.3

4.6 ± 7.0

Creatinine, (μmol/l)

60.0 to 273.0

60 to 273.0

63 to 177.0

0.23

117.1 ± 44.6

124.9 ± 53.6

107.5 ± 28.7

Iohexol clearance, (ml/min/1.7 m2)

6.4 to 91.0

18.0 to 78.0

6.4 to 91

0.33

51.3 ± 17.4

48.8 ± 16.0

54.4 ± 19.0