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Table 3 Results of scintigraphic and biochemical parameters in CSA and TAC groups at 1-year control

From: Cyclosporin A, but not tacrolimus, negatively affects the hepatic extraction fraction of hepatobiliary scintigraphy in liver transplant recipients

Parameters (range, average ± SD) Total (n  = 38) CSA at 1 year (n  = 21) TAC at 1 year (n  = 17) pvalue
HEF (%) 17 to 100 17 to 79 37 to 100 <0.0001
62.8 ± 29.0 44.7 ± 18.4 85.2 ± 23.6
Bilirubin (μmol/l) 3.0 to 146.0 4.0 to 146.0 3.0 to 142.0 0.88
18.5 ± 30.4 17.8 ± 29.9 19.4 ± 32.0
ALAT (μkat/l) 0.2 to 3.9 0.2 to 3.0 0.2 to 3.9 0.13
1.1 ± 1.0 0.8 ± 0.7 1.3 ± 1.2
ASAT (μkat/l) 0.3 to 3.0 0.3 to 2.4 0.3 to 3.0 0.38
0.9 ± 0.7 0.8 ± 0.5 1.0 ± 0.9
ALP (μkat/l) 0.7 to 5.8 0.7 to 5.8 0.8 to 4.8 0.44
1.8 ± 1.0 1.9 ± 1.4 1.7 ± 1.0
GT (μkat/l) 0.2 to 26.2 0.4 to 8.1 0.2 to 26.2 0.12
3.2 ± 5.1 2.1 ± 2.3 4.6 ± 7.0
Creatinine, (μmol/l) 60.0 to 273.0 60 to 273.0 63 to 177.0 0.23
117.1 ± 44.6 124.9 ± 53.6 107.5 ± 28.7
Iohexol clearance, (ml/min/1.7 m2) 6.4 to 91.0 18.0 to 78.0 6.4 to 91 0.33
51.3 ± 17.4 48.8 ± 16.0 54.4 ± 19.0