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Table 2 Results of scintigraphic and biochemical parameters in CSA and TAC groups at 3-month control

From: Cyclosporin A, but not tacrolimus, negatively affects the hepatic extraction fraction of hepatobiliary scintigraphy in liver transplant recipients

Parameters (range, average ± SD) Total (n  = 39) CSA at 3 months (n  = 24) TAC at 3 months (n  = 15) pvalue
HEF (%) 11 to 100 11 to 90 46 to 100 <0.0001
55.6 ± 31.6 35.8 ± 21.2 87.3 ± 14.8
Bilirubin (μmol/l) 2.0 to 59.0 5.0 to 59.0 2.0 to 38.0 0.02
Ref: <26 14.6 ± 12.6 18.1 ± 13.5 8.9 ± 8.4
ALAT (μkat/l) 0.1 to 1.6 0.1 to 1.6 0.2 to 1.0 0.57
Ref: <0.76 0.6 ± 0.3 0.6 ± 0.4 0.5 ± 0.2
ASAT (μkat/l) 0.2 to 2.5 0.2 to 2.5 0.2 to 1.2 0.33
Ref: <0.61 0.6 ± 0.4 0.7 ± 0.5 0.5 ± 0.2
ALP (μkat/l) 0.8 to 18.1 0.8 to 5.8 0.8 to 18.1 0.16
Ref: <1.9 2.1 ± 2.9 1.6 ± 1.2 3.0 ± 4.4
GT (μkat/l) 0.3 to 22.7 0.3 to 8.8 0.4 to 22.7 0.16
Ref: <1.3 2.8 ± 4.6 2.0 ± 2.3 4.1 ± 6.7
  1. CSA, cyclosporine A; TAC, tacrolimus; ALAT, alanine aminotransferase; ASAT, aspartate aminotransferase; ALP, alkaline phosphatase; GT, gamma-glutamyl transpeptidase.