Table 3 Radiation dosimetry estimates for [ ¹⁸  F]AFM using the means of four male and four female monkeys

Target organ

Adrenals^a

14.0 ± 0.1

16.8 ± 0.4

15.1 ± 1.4

Brain^a

12.8 ± 2.2

12.4 ± 1.2

12.7 ± 1.8

Breasts^a

9.0 ± 0.5

10.5 ± 0.5

9.5 ± 0.9

Gallbladder^a

12.6 ± 0.3

13.9 ± 0.8

13.1 ± 0.8

LLI wall^a

12.4 ± 0.8

15.2 ± 0.8

13.5 ± 1.6

Small intestine^a

12.4 ± 0.6

14.0 ± 0.8

13.0 ± 1.0

Stomach^a

11.3 ± 0.6

13.7 ± 0.8

12.2 ± 1.4

ULI wall^a

11.9 ± 0.6

14.5 ± 0.8

12.9 ± 1.4

Heart wall^a

21.0 ± 1.6

19.3 ± 1.0

20.3 ± 1.6

Kidneys^a

18.9 ± 1.3

21.8 ± 0.8

20.0 ± 1.9

Liver^a

15.7 ± 2.7

14.7 ± 1.8

15.3 ± 2.3

Lungs^a

36.6 ± 6.3

32.6 ± 4.6

35.1 ± 5.8

Muscle^a

10.0 ± 0.4

12.4 ± 0.5

10.9 ± 1.3

Ovaries^a

12.8 ± 0.8

15.2 ± 0.8

13.7 ± 1.4

Pancrease^a

13.1 ± 0.3

15.4 ± 0.7

14.0 ± 1.2

Red marrow^a

35.8 ± 4.8

34.7 ± 6.5

35.4 ± 5.1

Osteogenic cells^a

32.8 ± 4.8

49.5 ± 5.7

39.1 ± 9.8

Skin^a

7.6 ± 0.3

9.5 ± 0.4

8.3 ± 1.0

Spleen^a

11.0 ± 1.9

12.0 ± 0.6

11.4 ± 1.6

Testes^a

9.0 ± 0.8

-

9.0 ± 0.8

Thymus^a

11.5 ± 0.5

13.5 ± 0.6

12.3 ± 1.1

Thyroid^a

10.3 ± 0.5

12.1 ± 0.5

11.0 ± 1.0

Urinary bladder^a

23.1 ± 12.9

11.1 ± 0.7

18.6 ± 11.6

Uterus^a

12.6 ± 1.3

14.3 ± 0.8

13.3 ± 1.4

Total body^a

12.2 ± 0.1

15.3 ± 0.0

13.4 ± 1.6

Effective dose equivalent (EDE)^b

20.2 ± 0.5

20.6 ± 0.5

20.3 ± 0.5

Effective dose (ED)^b

18.0 ± 0.5

18.3 ± 0.4

18.2 ± 0.5