Figure 1

The three synthetic phantom configurations before (first row) and after reconstruction (second row). The presented reconstructed examples have a contrast of 8 to 1, 60-M emission counts and is reconstructed with OPTOF (2 iterations, 21 subsets, 2-mm post filter size) and 200 × 200 pixels matrix size; a) including 7 spheres with diameters of 7, 10, 13, 17, 22, 28 and 37 mm, b) including 7 spheres with necrotic core, outer diameters of 42 mm and inner diameters of 7, 10, 13, 17, 22, 28 and 37 mm, c) including 6 different lesion shapes extracted from real patient data.