Liver radioactivity after99mTc-MIBI injection in mice fed the normal and MCD diet for 2 and 4 weeks. (N =6 per group). (A) Time-activity curve of relative radioactivity. (B) AUC ratio compared to control. Radioactivity was normalized by liver peak activity. Data are expressed as mean ± SEM. Statistical difference was assessed using Dunnett's test. *p <0.05, **p <0.01 compared to the control mice.