Figure 3

Tumour control probability. TCP as a function of tumour mass at activities producing a TCP of 90% in a static 300-mg tumour, or an absorbed dose of 60 Gy when lower. The clonogenic tumour cell density was 10⁸/g and the LQ model parameters were α = 0.27 Gy⁻¹, α/β = 6 Gy and T_μ = 0.5 h. For the alpha-particle part of the dose by ²¹³Bi, RBE = 3.4. (A) Single-exponential clearance kinetics and (B) double-exponential clearance kinetics.