Axial images obtained after vascular injury. The imaging studies were performed 13 days post-stroke. The infarct volume evaluated on MRI was 13 cm3. (A) Flair T2-weighted MR image. Left fronto-insular hypersignal demonstrating infarcted tissue. (B) Post-gadolinium T1-weighted MR image. Enhancement signal in the left fronto-insular cortex corresponding to the breakdown of BBB. (C) Co-registration image obtained between the post-gadolinium T1 MRI and PET. Note the absence of 18 F-DPA-714 uptake by the multiple bilateral nodular hypersignals within the white matter in connection with leukoaraïosis lesions.