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EJNMMI Research
Figure 3 | EJNMMI Research

Figure 3

From: Synergism of peptide receptor-targeted Auger electron radiation therapy with anti-angiogenic compounds in a mouse model of neuroendocrine tumors

Figure 3

Subcellular localization of exendin-4 in cultivated tumor β-cells of Rip1Tag2 mice 2 h after injection. Tumor beta-cells were incubated with FAM-exendin-4 (A, green), anti-Lamp-2 (B, red, an anti-lysosome antibody), and nuclear DAPI stain (C, blue). Fluorescein-exendin-4 was internalized into the cytoplasm and into the nuclei of tumor beta-cells. However, there was only a minimal co-localization of FAM-exendin and Lamp-2 (D, merged picture).

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