Skip to main content

Table 1 Baseline and PET characteristics of controls and patients with DIPG

From: 18 F-FDG PET standard uptake values of the normal pons in children: establishing a reference value for diffuse intrinsic pontine glioma

  Controls DIPG
Number of subjects 36a 6
 Male 21 2
 Female 15 4
Median age (years) 12 (±4) 6 (±5)
 0 to 5 0 2
 6 to 10 15 3
 11 to 15 14 0
 16 to 20 5 1
 20 to 25 2 0
Anti-epileptic drugs   
 Valproic acid 3 0
 Clobazam 4 0
 Carbamazepine 12 0
 Levetiracetam 6 0
 Lamotrigine 9 0
 Other 3 0
Histology   
 Anaplastic astrocytoma   2 (biopsy)
 Glioblastoma multiforme   1 (autopsy)
 DIPG histology unknown   3
PET characteristics   
 Mean 18 F-FDG dose (MBq) 187 (±11) 170 (±29)
 Mean scan duration (min) 15 (±0) 16 (±2)
 15 min 35 5
 20 min 1 1
18 F-FDG uptake interval time   
 Mean (min) 48 (±16) 50 (±27)
PET reconstruction parameters   
 Method OSEM OSEM
 Matrix 256 34 6
 Matrix 128 2 0
  1. OSEM, ordered subset expectation maximization. aThe controls consisted of 6 subjects with temporal lobe, 1 with parietal lobe, and 2 with frontal lobe epileptogenic foci; 5 with hypometabolism of the hippocampus; 5 with focal cortical dysplasia; 3 with mesial temporal sclerosis; and 14 without structural or 18F-FDG PET epileptogenic foci.