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  1. About inflammation and infection: reply to Signore

    Anne Roivainen, Turku PET Centre, University of Turku and Turku University Hospital

    13 February 2013

    Anu Autio1, Sirpa Jalkanen2, Anne Roivainen1,3*
    * Corresponding author
    Email: anne.roivainen@utu.fi
    Author details
    1Turku PET Centre, University of Turku and Turku University Hospital,
    Kiinamyllynkatu 4-8, Turku 20521, Finland. 2MediCity Research Laboratory and
    Department of Medical Microbiology and Immunology, University of Turku,
    Turku 20520, Finland. 3Turku Center for Disease Modeling, University of
    Turku, Turku 20520, Finland.

    Dear Editor,
    We agree with Dr. Alberto Signore and his letter [1] nicely defines inflammation and infection, which we did not make clear enough in our review [2]. However, the endothelial molecules guiding the migration of leukocytes to sites of inflammation and infection are practically taken the same as infection always has inflammatory components. Therefore, it is highly unlikely that imaging endothelial molecules one can easily discriminate between infection and inflammation.

    References
    1. Signore A: About inflammation and infection. EJNMMI Res 2013, 3(1):8.

    2. Autio A, Jalkanen S, Roivainen A: Nuclear imaging of inflammation: homingassociated
    molecules as targets.
    EJNMMI Res 2013, 3(1):1.

    Competing interests

    The authors declare that they have no competing interests.

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