Figure 2
From: 18 F-click labeling and preclinical evaluation of a new 18 F-folate for PET imaging
Results of ex vivo biodistribution studies under control and blockade conditions using [18 F]12 in mice. The human KB tumor-bearing nude mice were euthanized 60 min post-injection. Data are expressed as percentage injected dose per gram tissue (%ID/g). In the blockade group (n = 3), 100 μg of native folic acid was injected into each animal 5 min prior to the radiotracer administration, whereas the control group (n = 3) received a corresponding volume of PBS.