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Table 1 Likelihood ratio test on analysis methods and model selection for U87

From: Factors affecting tumor 18 F-FDG uptake in longitudinal mouse PET studies

Response variable Model a Log likelihood Random parameters D d P d AIC c RSS
Standard c Mixed c
K i /RC 1 54.81 54.81 a 1.4 × 10−8 >0.99 −105.41 4.88 × 10−3
  2 55.00 54.82 a, c 0.368 0.947 −102.92 4.87 × 10−3
  3b 55.91 55.91 a 1.03 × 10−8 >0.99 −107.12 4.36 × 10−3
  4b 56.14 56.14 a 1.03 × 10−8 >0.99 −102.78 4.27 × 10−3
SUV/RC 1 −15.45 −15.45 a 4.3 × 10−9 >0.99 35.12 5.49
  2 −15.29 −14.53 a, c 1.53 0.675 37.29 5.41
  3b −13.10 −13.04 a 0.102 0.75 30.41 4.34
  4b −13.07 −13.04 a 0.0606 0.81 32.85 4.33
  1. aModels 1 to 4 correspond to Equations 6 to 9. bThese models were built with b set to 0. cStandard denotes the standard least-squares method, and mixed denotes the mixed-effects method. d D is the likelihood ratio statistic, and P is the significance level.