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EJNMMI Research
Figure 5 | EJNMMI Research

Figure 5

From: Imaging of the appearance time of cerebral blood using [15O]H2O PET for the computation of correct CBF

Figure 5

Sensitivities of ATB and CBF to errors in dispersion time constant and partition coefficient value. Results of the simulation study demonstrating the effects of errors of the assumed dispersion time constant of the arterial input function (A, C) and errors in the assumed partition coefficient (p, ml/g) (B, D) on the calculated appearance time of blood (ATB) (A, B) and the calculated cerebral blood flow (CBF) (C, D). Positive and negative values of errors in the time constant indicate undercorrection and overcorrection of dispersion time, respectively. Results are plotted for the autoradiography (ARG), the basis function methods with fixing partition coefficient (BFMF), the basis function methods without fixing partition coefficient (BFMP), and ATB correction (BFMAT). Δt, shifted time of appearance time of input.

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