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Table 2 Regional VT values among MS patients and healthy controls

From: In vivo TSPO imaging in patients with multiple sclerosis: a brain PET study with [18F]FEDAA1106

Region

Six MS naive

Three MS treatment (+)

Five HC

Mean

Min

Max

Mean

Min

Max

Mean

Min

Max

Whole gray matter

14.0

11.8

17.2

10.1

7.8

13.8

14.0

7.2

17.8

ACC

14.8

11.5

19.2

9.7

7.3

14.4

13.8

5.9

19.4

Caudate

12.8

10.5

16.2

10.2

8.0

14.1

13.5

7.5

17.3

Putamen

14.7

12.0

18.6

9.4

7.8

12.0

13.5

8.1

16.9

Thalamus

15.3

13.2

20.6

13.3

9.5

20.3

15.9

6.4

19.3

Cerebellum

14.9

12.6

17.6

10.5

8.4

14.3

14.1

7.4

18.6

Frontal cortex

14.9

12.9

17.2

10.7

8.1

14.6

14.7

7.3

19.1

Hippocampus

12.8

10.1

14.5

12.1

7.3

21.1

11.5

6.2

14.0

Insular cortex

14.1

12.3

19.0

10.7

8.3

14.2

13.9

7.2

19.8

Lateral temporal cortex

14.2

11.8

17.6

9.8

8.1

13.0

14.1

7.4

17.8

Midbrain

14.4

9.7

22.4

11.0

7.3

18.0

10.9

6.6

13.8

Occipital cortex

14.6

11.9

18.6

10.1

7.4

13.1

14.5

8.0

18.8

Orbitofrontal cortex

19.4

12.0

44.5

10.8

8.3

14.5

14.7

7.8

20.2

Parietal cortex

14.4

12.4

18.2

9.8

7.4

13.3

14.1

7.2

18.5

PCC

16.2

12.7

25.2

11.9

8.0

19.6

15.8

8.4

23.2

Pons

13.7

11.3

17.7

18.0

7.9

38.0

12.9

10.2

15.6

  1. There was no significant difference of the VT values in any region among the three groups.