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EJNMMI Research

Table 1 Radiochemical yields of automated 68 Ga labeling, and corresponding calculated minimal A S of radiopharmaceutical formulations

From: Comparative gallium-68 labeling of TRAP-, NOTA-, and DOTA-peptides: practical consequences for the future of gallium-68-PET

Precursor amount (nmol)

Product yield (%)

Specific activity (GBq/μmol)

68Ga-TRAP(RGD)3

0.017

27.9 ± 16.0

12059 ± 6922

0.04

42.9 ± 14.0

7889 ± 2567

0.1

65.8 ± 5.6

4848 ± 414

0.33

90.0 ± 2.7

2006 ± 61

1

95.2 ± 1.7

701 ± 12

10

97.8 ± 0.5

73 ± 0.4

68Ga-DOTATOC

0.6

34.4 ± 21.3

422 ± 261

2.2

63.7 ± 13.5

213 ± 45

7

82.8 ± 8.7

87 ± 9

14

88.0 ± 2.1

46 ± 1.1

68Ga-NODAGA-RGD

0.22

31.7 ± 28.4

1059 ± 951

0.4

51.9 ± 22.8

954 ± 419

1

74.1 ± 15.2

545 ± 112

2

85.0 ± 7.4

313 ± 28

6

94.7 ± 1.1

116 ± 1.3

20.5

93.7 ± 1.9

34 ± 0.7

  1. At typical time of injection (30 min after start of synthesis), values given as mean ± SD.
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