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Table 1 Radiochemical yields of automated 68 Ga labeling, and corresponding calculated minimal A S of radiopharmaceutical formulations

From: Comparative gallium-68 labeling of TRAP-, NOTA-, and DOTA-peptides: practical consequences for the future of gallium-68-PET

Precursor amount (nmol) Product yield (%) Specific activity (GBq/μmol)
68Ga-TRAP(RGD)3
0.017 27.9 ± 16.0 12059 ± 6922
0.04 42.9 ± 14.0 7889 ± 2567
0.1 65.8 ± 5.6 4848 ± 414
0.33 90.0 ± 2.7 2006 ± 61
1 95.2 ± 1.7 701 ± 12
10 97.8 ± 0.5 73 ± 0.4
68Ga-DOTATOC
0.6 34.4 ± 21.3 422 ± 261
2.2 63.7 ± 13.5 213 ± 45
7 82.8 ± 8.7 87 ± 9
14 88.0 ± 2.1 46 ± 1.1
68Ga-NODAGA-RGD
0.22 31.7 ± 28.4 1059 ± 951
0.4 51.9 ± 22.8 954 ± 419
1 74.1 ± 15.2 545 ± 112
2 85.0 ± 7.4 313 ± 28
6 94.7 ± 1.1 116 ± 1.3
20.5 93.7 ± 1.9 34 ± 0.7
  1. At typical time of injection (30 min after start of synthesis), values given as mean ± SD.