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Table 2 Organ distribution (1 h post-injection) of [ 68 Ga]6 and [ 68 Ga]7 in BALB/c nu/nu mice

From: A dimerized urea-based inhibitor of the prostate-specific membrane antigen for 68Ga-PET imaging of prostate cancer

Organ Monomer [ 68Ga]6 Dimer [ 68Ga]7
Blood 0.53 ± 0.04 0.31 ± 0.03
Heart 0.83 ± 0.08 0.90 ± 0.12
Lung 2.36 ± 0.27 2.25 ± 0.24
Spleen 17.90 ± 2.87 17.88 ± 4.53
Liver 1.43 ± 0.19 1.29 ± 0.11
Kidney 139.44 ± 21.40 133.43 ± 18.88
Muscle 1.00 ± 0.24 0.90 ± 0.01
Intestine 1.14 ± 0.46 0.57 ± 0.14
Brain 0.40 ± 0.19 0.17 ± 0.01
PC-3 tumor 1.30 ± 0.12 0.93 ± 0.53
LNCaP tumor (n = 5) 4.89 ± 1.34 8.22 ± 1.78
  1. Injection dose was 1 to 2 MBq/mouse, 0.1 to 0.2 nmol. Data are expressed as % ID/g ± SD, n = 3.
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