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Table 2 Organ distribution (1 h post-injection) of [ 68 Ga]6 and [ 68 Ga]7 in BALB/c nu/nu mice

From: A dimerized urea-based inhibitor of the prostate-specific membrane antigen for 68Ga-PET imaging of prostate cancer

Organ

Monomer [ 68Ga]6

Dimer [ 68Ga]7

Blood

0.53 ± 0.04

0.31 ± 0.03

Heart

0.83 ± 0.08

0.90 ± 0.12

Lung

2.36 ± 0.27

2.25 ± 0.24

Spleen

17.90 ± 2.87

17.88 ± 4.53

Liver

1.43 ± 0.19

1.29 ± 0.11

Kidney

139.44 ± 21.40

133.43 ± 18.88

Muscle

1.00 ± 0.24

0.90 ± 0.01

Intestine

1.14 ± 0.46

0.57 ± 0.14

Brain

0.40 ± 0.19

0.17 ± 0.01

PC-3 tumor

1.30 ± 0.12

0.93 ± 0.53

LNCaP tumor (n = 5)

4.89 ± 1.34

8.22 ± 1.78

  1. Injection dose was 1 to 2 MBq/mouse, 0.1 to 0.2 nmol. Data are expressed as % ID/g ± SD, n = 3.