Figure 1

Schematic diagrams of the compartment models. In the upper diagram, a standard single-tissue compartment (1T2k) is shown. In this study, two different implementations were used: the 1T2k⁶⁰ model using 60 min of data acquisition and the 1T2k¹⁰ model using the first 10 min of data acquisition. In the lower diagram a standard two-tissue compartment (2T4k) model is shown. In this study, two different implementations were used: the 2T4k model without and the 2T4k^VTnsfix model with fixation of K ₁/k ₂ to the whole brain grey matter value. C, compartment.