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Table 5 Common biological processes

From: Effects of internal low-dose irradiation from 131I on gene expression in normal tissues in Balb/c mice

Tissue combination Biological process
Kidney cortex-kidney medulla Amiloride transport
  Amino acid transport
  Bone remodeling
  Canalicular bile acid transport
  Choline metabolism
  Negative regulation of cell adhesion
  Negative regulation of enzyme activity
  Positive regulation of actin filament polymerization
  Protection from natural killer cell mediated cytotoxicity
  Regulation of hormone secretion
Kidney cortex-liver Acetyl-CoA metabolism
  Response to sterol depletion
  Retinoid metabolism
  Steroid biosynthesis
Kidney cortex-lung Cellular response to starvation
  Cytoskeleton organization and biogenesis
  Fatty acid oxidation
  Patterning of blood vessels
  Positive regulation of glucose import
  Positive regulation of lipid metabolism
  Protein folding
  Regulation of transcription from RNA polymerase II promoter
Kidney cortex-spleen Regulation of axon extension
  Regulation of neuronal synaptic plasticity
  Response to oxidative stress
  Ubiquitin-dependent protein catabolism
Kidney medulla-liver Digestion
Kidney medulla-lung Cell migration
  Cell-matrix adhesion
  Cellular defense response
  Positive regulation of angiogenesis
  Positive regulation of neurotransmitter secretion
  Regulation of locomotion
  Regulation of long-term neuronal synaptic plasticity
  Response to hypoxia
  Synaptic vesicle transport
Kidney medulla-spleen Cartilage condensation
  Central nervous system development
  Complement activation; alternative pathway
  Neuropeptide signaling pathway
  Positive regulation of small GTPase mediated signal transduction
  Response to nutrient
  S-adenosylmethionine biosynthesis
Liver-lung Embryonic heart tube development
  Fatty acid metabolism
Liver-spleen Negative regulation of signal transduction
  Regulation of cell growth
Lung-spleen Iron ion homeostasis
  Peptidoglycan metabolism
  Response to biotic stimulus
Kidney cortex-kidney medulla-lung Negative regulation of apoptosis
Kidney cortex-kidney medulla-spleen Defense response
Kidney cortex-liver-lung Acute-phase response
  Complement activation
  Lipid metabolism
Kidney cortex-lung-spleen Response to glucose stimulus
Kidney medulla-lung-spleen Positive regulation of non-apoptotic programmed cell death
Liver-lung-spleen Response to heat
  Response to unfolded protein
Kidney cortex-kidney medulla-liver-lung Electron transport
Kidney cortex-kidney medulla-lung-spleen Inflammatory response
  Negative regulation of gluconeogenesis
  Negative regulation of lipoprotein lipase activity
  Positive regulation of fatty acid metabolism
  Positive regulation of signal transduction
Kidney cortex-kidney medulla-liver-lung-spleen Immune response
  1. Biological processes affected in two or more tissues independent of the absorbed dose. All processes had a p value < 0.05. Additional information is presented in Additional file 1.