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Table 2 Total number of regulated transcripts in 131I irradiated tissues

From: Effects of internal low-dose irradiation from 131I on gene expression in normal tissues in Balb/c mice

   Number of transcripts regulated per injected activity
  Total number of transcripts regulated 13 kBq 131 I 130 kBq 131 I 260 kBq 131 I
Kidney medulla 423 160 ↑50 (31%) 158 ↑65 (41%) 208 ↑65 (31%)
    ↓110 (69%)   ↓93 (59%)   ↓143 (69%)
Kidney cortex 260 154 ↑87 (56%) 85 ↑30 (35%) 93 ↑60 (65%)
    ↓67 (44%)   ↓55 (65%)   ↓33 (35%)
Liver 738 417 ↑250 (60%) 427 ↑264 (62%) 455 ↑292 (64%)
    ↓167(40%)   ↓163(38%)   ↓163(36%)
Lung 857 320 ↑149(47%) 113 ↑82(73%) 596 ↑475(80%)
    ↓171(53%)   ↓31(27%)   ↓121(20%)
Spleen 607 240 ↑158(66%) 306 ↑240(78%) 238 ↑176(74%)
    ↓82(34%)   ↓66(22%)   ↓62(26%)
  1. Data on changes in gene expression after i.v. injection of 13, 130, or 260 kBq. The total number of transcripts regulated in the tissues investigated is given together with the number of up- (arrows pointing up) and downregulated (arrows pointing down) transcripts given as the total number and percentage (in parentheses).