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Table 2 Level of TS1 staining in selected regions of primary bronchial small-cell carcinoma biopsies

From: Binding of TS1, an anti-keratin 8 antibody, in small-cell lung cancer after 177Lu-DOTA-Tyr3-octreotate treatment: a histological study in xenografted mice

Case Image 1 Image 2 Image 3 Image 4 Image 5 Image 6 Image 7 Image 8 Image 9
1 17.9 45.2 44.1 12.3 8.6 41.8 31.6 - -
2 44.9 19.0 16.1 - - - - - -
3 8.0 5.5 - - - - - - -
4 4.7 5.1 - - - - - - -
5 31.0 22.9 430 32.9 68.7 58.9 71.0 60.8 49.5
6 9.9 15.7 3.3 4.4 - - - - -
7 81.7a 11.6 9.0 11.2 13.1 14.4 - - -
  1. The biopsies had approximately the same size 10-20 mm2 but the number of areas with tumour cells and necrotic tissue varied. Between two to nine 320 × 250-μm areas with tumour cells, necrotic tissue, and high TS1 binding per case were analysed. The percentage (%) DAB-positive immunostaining for TS1 in seven cases of primary bronchial small-cell carcinomas was determined by use of ImageJ ImmunoRatio.aContains many intact tumour cells.