Treatment | Dosage | 500 mm 3 | 1,000 mm 3 | ||
---|---|---|---|---|---|
Days a | Growth delay b | Days | Growth delay | ||
NaCl | 15 ± 7 | 0 ± 10 | 25 ± 7 | 0 ± 11 | |
Trastuzumab (pooled) | 20 - 250 μg | 15 ± 7 | 0 ± 11 | 23 ± 8 | -2 ± 12 |
227Th-rituximab | 400 and 600 kBq/kg | 15 ± 8 | -3 ± 11 | 27 ± 10 | 2 ± 11 |
227Th-trastuzumab | 200 kBq/kg | 22 ± 8 | 7 ± 11 | 32 ± 8 | 7 ± 12 |
227Th-trastuzumab | 400 kBq/kg | 38 ± 8 | 23 ± 10 | 70 ± 10 | 45 ± 12 |
227Th-trastuzumab | 600 kBq/kg | 60 ± 7 | 45 ± 7 | 90 ± 10 | 65 ± 7 |