Predictive value of 99mTc-MAA-based dosimetry in personalized 90Y-SIRT planning for liver malignancies

EJNMMI Research

Table 4 Values of TNR (TNR-NTLt and TNR-NTLw) for simulation (^99mTc-MAA) and therapy (⁹⁰Y) across the different tumoral liver volumes

Segment	TNR	^99mTc-MAA	⁹⁰Y	Wilcoxon p-value	Pearson's r correlation	Bland–Altman Bias [95% CI]
TL	TL/NTLt	3.14 ± 3.42	2.28 ± 1.94	0.05*	0.86 (P < .001)	− 0.86 [− 4.82; 3.09]
TL	TL/NTLw	5.45 ± 6.00	3.42 ± 2.78	0.01*	0.86 (P < .001)	− 2.02 [− 9.61; 5.56]
TL ≤ 200 ml	TL/NTLt	3.54 ± 4.20	2.71 ± 2.43	0.38	0.94 (P < .001)	− 0.82 [− 4.87; 3.21]
TL ≤ 200 ml	TL/NTLw	6.37 ± 7.71	4.11 ± 3.55	0.15	0.90 (P < .001)	− 2.26 [− 11.64; 7.11]
TL > 200 ml	TL/NTLt	2.76 ± 2.41	1.83 ± 1.10	0.04*	0.57 (P < .001)	− 0.93 [− 4.85; 2.98]
TL > 200 ml	TL/NTLw	4.58 ± 3.43	2.73 ± 1.41	0.02*	0.67 (P < .001)	− 1.85 [− 7.13; 3.43]