Fig. 1

Followed workflow. The acquired images are the pre-treatment diagnostic CT or MR and the SPECT and AC-CT from both simulation and therapy. For the post-therapeutic verification, segmentation and registration is performed. From these images, we proceed to calculate the activity map and then, the dose map based on self-calibration strategy and the local energy deposition approach. Finally, the MAD, DVH and TNR are calculated within the three VOIs