Mitochondrial complex I density is associated with IQ and cognition in cognitively healthy adults: an in vivo [18F]BCPP-EF PET study

Shatalina, Ekaterina; Whitehurst, Thomas S.; Onwordi, Ellis Chika; Gilbert, Barnabas J.; Rizzo, Gaia; Whittington, Alex; Mansur, Ayla; Tsukada, Hideo; Marques, Tiago Reis; Natesan, Sridhar; Rabiner, Eugenii A.; Wall, Matthew B.; Howes, Oliver D.

doi:10.1186/s13550-024-01099-1

Fig. 3

From: Mitochondrial complex I density is associated with IQ and cognition in cognitively healthy adults: an in vivo [¹⁸F]BCPP-EF PET study

Pearson’s correlation coefficients for clusters where [¹⁸F]BCPP-EF DVR_CS−1 was significantly correlated with WAIS-IV predicted IQ (3A), WAIS-IV symbol-digit substitution scores (3B), WAIS-IV arithmetic scores (3C) (n = 16, Pearson’s correlation, Z > 2.3, cluster threshold p < 0.05). Axial slices in MNI152 are: -12 -2 8 18 28; 38 48 56 66 76, results are shown in neurological format (L = L).

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